Tearing down the spindle

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Tearing down the spindle

isassembly of the mitotic spindle takes some effort, according to Kan Cao, Yixian Zheng (Johns Hopkins University, Baltimore, MD), and colleagues, who show that an ATPase and its binding partners pull apart the spindle. The spindle is put together by assembly factors that are activated by the cyclin-dependent kinase Cdc2. The loss of Cdc2 activity at the end of mitosis has thus been the convent...

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ژورنال

عنوان ژورنال: Journal of Cell Biology

سال: 2003

ISSN: 1540-8140,0021-9525

DOI: 10.1083/jcb1634rr1